The article is devoted to the research of the main directions of development of the antitrust compliance of an economic entity as a new institution of competition law. The author analyzed scientific approaches to the introduction of the antitrust compliance system into the structure of corporate governance of commercial corporations, as well as the guidelines of the US Department of Justice and the European Commission. Particular attention in the article was paid to the analysis of key regulatory legal acts and established practice of the FAS Russia in this area. It is argued that antitrust compliance is an integral element of the corporate governance system aimed at reducing the antitrust risks of an economic entity and forming a legal culture of compliance with antitrust requirements by its employees. It is argued that voluntariness is the basis for the implementation of an effective system of antitrust compliance, which corresponds to generally accepted approaches that exist in world practice. The consequences of independent disclosure of a violation by an economic entity by applying the antitrust compliance system in the form of exemption and mitigation of administrative responsibility are determined.